.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_4GR-T1-TDNA-1_A23MHWWLT4_1;L002;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ff/e5d8f31fa5d9aac14b55f6de8f3b53/.command.log
Size: 325.2 KB
Task: DAQ:SENTIEON_BWAMEM (1136_4GR-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/ea21ff7199417a10bacb1db911320d/1136_4GR-T1-TDNA-1_A23MHWWLT4_1/1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ff/e5d8f31fa5d9aac14b55f6de8f3b53/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ff/e5d8f31fa5d9aac14b55f6de8f3b53/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/ea21ff7199417a10bacb1db911320d/1136_4GR-T1-TDNA-1_A23MHWWLT4_1/1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2615.191 CPU sec, 108.997 real sec
[M::process] read 701216 sequences (100000019 bp) in 1.401 CPU sec, 1.407 real sec...
[M::process] read 699474 sequences (100000079 bp) in 2.109 CPU sec, 2.128 real sec...
[M::process] read 698764 sequences (100000094 bp) in 1.824 CPU sec, 1.842 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285246, 31, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 305, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (263.69, 112.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (258.14, 129.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 263, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (646.03, 951.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 331, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (307.38, 158.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698194 sequences (100000249 bp) in 1.594 CPU sec, 1.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284078, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 320, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (334.05, 243.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (266.24, 134.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 958, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3575)
[M::mem_pestat] mean and std.dev: (722.53, 593.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 326, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (332.89, 200.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284427, 34, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 425, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (441.93, 292.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.46, 133.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (904, 1512, 2702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6298)
[M::mem_pestat] mean and std.dev: (1369.41, 866.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (650.32, 652.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701216 reads in 330.194 CPU sec, 10.626 real sec
[M::mem_process_seqs] Processed 698764 reads in 223.686 CPU sec, 7.278 real sec
[M::mem_process_seqs] Processed 699474 reads in 247.121 CPU sec, 8.020 real sec
sorting block 0, #reads = 1078143 mem = 536878647 peak = 568868864
[M::process] read 697952 sequences (100000183 bp) in 3.340 CPU sec, 3.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283627, 29, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 271, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1501)
[M::mem_pestat] mean and std.dev: (356.15, 290.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.13, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (623, 776, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (1013.04, 730.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 674, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331)
[M::mem_pestat] mean and std.dev: (1672.77, 2093.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697234 sequences (100000225 bp) in 2.265 CPU sec, 2.374 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283871, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 246, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5578)
[M::mem_pestat] mean and std.dev: (905.66, 1164.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.25, 137.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 486, 3776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10926)
[M::mem_pestat] mean and std.dev: (2484.74, 3100.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 533, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4279)
[M::mem_pestat] mean and std.dev: (875.42, 874.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698194 reads in 200.401 CPU sec, 6.383 real sec
sorting block 1, #reads = 1077277 mem = 536881092 peak = 752381952
[M::mem_process_seqs] Processed 697952 reads in 131.622 CPU sec, 4.154 real sec
[M::process] read 697118 sequences (100000056 bp) in 2.050 CPU sec, 2.137 real sec...
sorting block 2, #reads = 1077295 mem = 536879813 peak = 752381952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283982, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 382, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1520)
[M::mem_pestat] mean and std.dev: (415.92, 262.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.54, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 1008, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999)
[M::mem_pestat] mean and std.dev: (1047.10, 978.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 228, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (313.42, 240.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696362 sequences (100000099 bp) in 2.752 CPU sec, 2.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283649, 37, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 359, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (357.13, 309.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.04, 139.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 476, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (795.36, 807.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 337, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (497.59, 392.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696138 sequences (100000300 bp) in 2.003 CPU sec, 2.011 real sec...
[M::mem_process_seqs] Processed 697234 reads in 209.033 CPU sec, 6.666 real sec
[M::mem_process_seqs] Processed 697118 reads in 133.579 CPU sec, 4.245 real sec
sorting block 3, #reads = 1077046 mem = 536882683 peak = 752381952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283851, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 380, 2003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5493)
[M::mem_pestat] mean and std.dev: (1088.09, 1510.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (275.02, 139.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 697, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (654.52, 386.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 350, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (442.91, 438.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695746 sequences (100000222 bp) in 3.498 CPU sec, 3.730 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283394, 29, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 510, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (598.98, 517.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.83, 140.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 1049, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6472)
[M::mem_pestat] mean and std.dev: (1176.96, 1203.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 344, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (344.62, 228.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696362 reads in 197.027 CPU sec, 6.288 real sec
[M::process] read 695842 sequences (100000206 bp) in 1.800 CPU sec, 1.800 real sec...
[M::mem_process_seqs] Processed 696138 reads in 132.648 CPU sec, 4.551 real sec
sorting block 4, #reads = 1077134 mem = 536878852 peak = 752381952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283319, 34, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 304, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (300.00, 207.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.68, 140.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 706, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (625.04, 411.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 317, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (706.48, 599.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696188 sequences (100000021 bp) in 2.730 CPU sec, 2.943 real sec...
[M::process] read 696462 sequences (100000254 bp) in 1.837 CPU sec, 1.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283025, 32, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 303, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (551.82, 642.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.79, 140.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 912, 2106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6004)
[M::mem_pestat] mean and std.dev: (1380.50, 1244.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 206, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (304.71, 236.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695746 reads in 214.375 CPU sec, 7.198 real sec
sorting block 5, #reads = 1076860 mem = 536879207 peak = 752381952
[M::mem_process_seqs] Processed 695842 reads in 137.574 CPU sec, 4.401 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282931, 28, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 720, 2480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6740)
[M::mem_pestat] mean and std.dev: (1481.12, 1585.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.55, 139.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 294, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (411.89, 370.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (543, 725, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (669.38, 358.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1074967 mem = 536877914 peak = 807546880
[M::process] read 696364 sequences (100000197 bp) in 3.214 CPU sec, 3.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283121, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 360, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (498.88, 428.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.81, 138.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 349, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (838.13, 844.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 368, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (499.68, 415.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696480 sequences (100000293 bp) in 1.969 CPU sec, 1.967 real sec...
[M::mem_process_seqs] Processed 696188 reads in 207.245 CPU sec, 6.625 real sec
[M::mem_process_seqs] Processed 696462 reads in 146.960 CPU sec, 4.704 real sec
sorting block 7, #reads = 1075950 mem = 536880273 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284003, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 295, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (412.40, 314.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.22, 137.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 423, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004)
[M::mem_pestat] mean and std.dev: (654.71, 743.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 427, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (609.57, 516.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695966 sequences (100000089 bp) in 3.942 CPU sec, 4.302 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283580, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 259, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (563.05, 538.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.60, 138.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 637, 3137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9003)
[M::mem_pestat] mean and std.dev: (1344.52, 1498.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 364, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (488.21, 400.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696364 reads in 206.182 CPU sec, 6.592 real sec
[M::mem_process_seqs] Processed 696480 reads in 135.245 CPU sec, 4.279 real sec
[M::process] read 695838 sequences (100000123 bp) in 3.542 CPU sec, 3.788 real sec...
sorting block 8, #reads = 1075870 mem = 536880244 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283291, 18, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 313, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (643.35, 706.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.40, 138.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 397, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (437.12, 351.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 393, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3475)
[M::mem_pestat] mean and std.dev: (831.44, 713.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695708 sequences (100000066 bp) in 3.348 CPU sec, 3.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283098, 31, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 569, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4259)
[M::mem_pestat] mean and std.dev: (980.61, 881.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (274.09, 138.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 591, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4874)
[M::mem_pestat] mean and std.dev: (925.87, 972.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6459)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 380, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (654.30, 561.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695966 reads in 207.788 CPU sec, 6.676 real sec
[M::mem_process_seqs] Processed 695838 reads in 136.995 CPU sec, 4.348 real sec
sorting block 9, #reads = 1075857 mem = 536879217 peak = 807546880
[M::process] read 694378 sequences (100000068 bp) in 2.662 CPU sec, 2.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283609, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 755, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4064)
[M::mem_pestat] mean and std.dev: (879.65, 785.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.30, 138.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 524, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4981)
[M::mem_pestat] mean and std.dev: (977.84, 1097.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 368, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (522.25, 487.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1076638 mem = 536876921 peak = 807546880
[M::process] read 695064 sequences (100000143 bp) in 3.051 CPU sec, 3.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282459, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 393, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3898)
[M::mem_pestat] mean and std.dev: (700.29, 738.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (278.56, 139.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 350, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (358.60, 301.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 360, 1878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5222)
[M::mem_pestat] mean and std.dev: (1090.89, 1301.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695708 reads in 199.227 CPU sec, 6.403 real sec
[M::mem_process_seqs] Processed 694378 reads in 132.941 CPU sec, 4.227 real sec
[M::process] read 694498 sequences (100000179 bp) in 2.762 CPU sec, 2.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282810, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 405, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (432.15, 277.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.21, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 419, 1953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5425)
[M::mem_pestat] mean and std.dev: (1033.32, 1093.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 455, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641)
[M::mem_pestat] mean and std.dev: (519.02, 381.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1077466 mem = 536877974 peak = 807546880
[M::process] read 694696 sequences (100000144 bp) in 3.178 CPU sec, 3.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282824, 35, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 677, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (727.74, 510.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.60, 138.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 568, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (1004.76, 1088.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 375, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (577.06, 508.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695064 reads in 203.298 CPU sec, 6.521 real sec
[M::process] read 694556 sequences (100000256 bp) in 2.151 CPU sec, 2.220 real sec...
[M::mem_process_seqs] Processed 694498 reads in 136.104 CPU sec, 4.424 real sec
sorting block 12, #reads = 1075745 mem = 536879533 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282612, 17, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (752.18, 900.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.72, 136.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (556, 971, 2220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5548)
[M::mem_pestat] mean and std.dev: (1155.41, 847.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 270, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (502.22, 461.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694390 sequences (100000280 bp) in 3.008 CPU sec, 3.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282122, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 408, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (618.03, 543.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (278.30, 139.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 715, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3818)
[M::mem_pestat] mean and std.dev: (866.04, 822.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 317, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (332.43, 182.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694696 reads in 205.885 CPU sec, 6.705 real sec
[M::mem_process_seqs] Processed 694556 reads in 137.612 CPU sec, 4.375 real sec
[M::process] read 694018 sequences (100000138 bp) in 2.819 CPU sec, 2.914 real sec...
sorting block 13, #reads = 1075804 mem = 536881669 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282741, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 428, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (872.56, 979.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (279.43, 140.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (677, 719, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (745.94, 431.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 288, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (332.64, 183.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696108 sequences (100000087 bp) in 2.892 CPU sec, 3.073 real sec...
sorting block 14, #reads = 1076529 mem = 536880465 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282829, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 336, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4662)
[M::mem_pestat] mean and std.dev: (734.92, 764.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (282.20, 142.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 591, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (563.25, 345.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 241, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (304.95, 237.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694390 reads in 198.201 CPU sec, 6.354 real sec
[M::process] read 699728 sequences (100000147 bp) in 2.131 CPU sec, 2.171 real sec...
[M::mem_process_seqs] Processed 694018 reads in 134.731 CPU sec, 4.268 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283040, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 389, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (563.49, 524.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.05, 137.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 636, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (561.00, 373.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 664, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4253)
[M::mem_pestat] mean and std.dev: (876.57, 756.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1075399 mem = 536879034 peak = 807546880
[M::process] read 699262 sequences (100000280 bp) in 3.252 CPU sec, 3.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284378, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 341, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (329.31, 147.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.38, 133.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 832, 2161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5377)
[M::mem_pestat] mean and std.dev: (1283.38, 1119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 339, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (445.35, 391.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698552 sequences (100000181 bp) in 1.751 CPU sec, 1.756 real sec...
[M::mem_process_seqs] Processed 696108 reads in 205.247 CPU sec, 6.559 real sec
[M::mem_process_seqs] Processed 699728 reads in 135.991 CPU sec, 4.360 real sec
sorting block 16, #reads = 1074903 mem = 536878317 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284504, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 390, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (320.89, 141.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.33, 136.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 359, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (664.74, 675.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (543.34, 563.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698242 sequences (100000111 bp) in 3.708 CPU sec, 4.009 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283723, 14, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 335, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (574.61, 643.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (269.51, 138.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 778, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4586)
[M::mem_pestat] mean and std.dev: (987.64, 920.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 290, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3787)
[M::mem_pestat] mean and std.dev: (610.33, 741.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699262 reads in 198.520 CPU sec, 6.385 real sec
[M::mem_process_seqs] Processed 698552 reads in 131.719 CPU sec, 4.166 real sec
[M::process] read 697512 sequences (100000038 bp) in 2.459 CPU sec, 2.567 real sec...
sorting block 17, #reads = 1080573 mem = 536877608 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283897, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 495, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (649.10, 621.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (271.00, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 1527, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (1306.78, 1214.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6677)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 701, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4779)
[M::mem_pestat] mean and std.dev: (610.70, 529.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697238 sequences (100000145 bp) in 3.167 CPU sec, 3.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284055, 14, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 366, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (359.26, 208.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.54, 140.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 705, 3169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9357)
[M::mem_pestat] mean and std.dev: (1426.00, 1463.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 413, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4372)
[M::mem_pestat] mean and std.dev: (831.42, 947.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698242 reads in 198.594 CPU sec, 6.362 real sec
sorting block 18, #reads = 1079228 mem = 536878069 peak = 807546880
[M::mem_process_seqs] Processed 697512 reads in 133.128 CPU sec, 4.210 real sec
[M::process] read 696606 sequences (100000251 bp) in 2.577 CPU sec, 2.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283916, 17, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 382, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (514.42, 395.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.09, 140.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 579, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (760.41, 647.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 438, 2370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6580)
[M::mem_pestat] mean and std.dev: (1206.64, 1116.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1079072 mem = 536883147 peak = 807546880
[M::process] read 696422 sequences (100000046 bp) in 3.139 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283756, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 885, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5802)
[M::mem_pestat] mean and std.dev: (1085.16, 867.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.57, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 524, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (693.95, 541.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 374, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (553.37, 495.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697238 reads in 199.682 CPU sec, 6.396 real sec
[M::mem_process_seqs] Processed 696606 reads in 132.253 CPU sec, 4.183 real sec
[M::process] read 696402 sequences (100000297 bp) in 2.501 CPU sec, 2.608 real sec...
sorting block 20, #reads = 1078127 mem = 536879237 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283481, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 422, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4532)
[M::mem_pestat] mean and std.dev: (911.12, 1136.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.76, 142.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 845, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (1113.50, 912.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 427, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (443.11, 333.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695728 sequences (100000113 bp) in 3.579 CPU sec, 3.931 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283547, 32, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 407, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6257)
[M::mem_pestat] mean and std.dev: (1030.38, 1294.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (277.31, 142.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 884, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (764.23, 737.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 644, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2998)
[M::mem_pestat] mean and std.dev: (646.20, 527.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696422 reads in 194.768 CPU sec, 6.249 real sec
[M::mem_process_seqs] Processed 696402 reads in 128.976 CPU sec, 4.088 real sec
sorting block 21, #reads = 1077759 mem = 536880383 peak = 807546880
[M::process] read 695656 sequences (100000191 bp) in 3.674 CPU sec, 4.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283407, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 334, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (373.33, 249.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (277.96, 142.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 1009, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (1076.15, 746.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 369, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (498.47, 374.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283330, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 269, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4821)
[M::mem_pestat] mean and std.dev: (790.53, 1042.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.64, 142.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 454, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (689.17, 595.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 326, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (307.74, 113.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695728 reads in 192.380 CPU sec, 6.258 real sec
[M::mem_process_seqs] Processed 695656 reads in 128.045 CPU sec, 4.116 real sec
[M::process] read 696238 sequences (100000015 bp) in 3.741 CPU sec, 4.156 real sec...
sorting block 22, #reads = 1076917 mem = 536888708 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283311, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 272, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (384.45, 368.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (275.06, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 912, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (685.90, 568.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 330, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (541.23, 495.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696562 sequences (100000162 bp) in 3.063 CPU sec, 3.410 real sec...
[M::mem_process_seqs] Processed 696238 reads in 106.982 CPU sec, 3.983 real sec
sorting block 23, #reads = 1076159 mem = 536878247 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283017, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 424, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (472.79, 336.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.21, 139.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 1693, 2194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5968)
[M::mem_pestat] mean and std.dev: (1222.00, 882.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 271, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (380.44, 315.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696406 sequences (100000218 bp) in 3.811 CPU sec, 4.137 real sec...
[M::mem_process_seqs] Processed 696562 reads in 111.542 CPU sec, 4.077 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282950, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 666, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4205)
[M::mem_pestat] mean and std.dev: (975.76, 939.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.26, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 529, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (713.80, 792.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 536, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (629.90, 512.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696510 sequences (100000246 bp) in 3.071 CPU sec, 3.394 real sec...
[M::mem_process_seqs] Processed 696406 reads in 109.035 CPU sec, 3.787 real sec
sorting block 24, #reads = 1076770 mem = 536880152 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283429, 33, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 376, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4096)
[M::mem_pestat] mean and std.dev: (669.66, 742.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.83, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 620, 2473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7111)
[M::mem_pestat] mean and std.dev: (1402.59, 1324.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9430)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 568, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5183)
[M::mem_pestat] mean and std.dev: (904.00, 815.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696300 sequences (100000145 bp) in 3.279 CPU sec, 3.604 real sec...
[M::mem_process_seqs] Processed 696510 reads in 109.087 CPU sec, 3.628 real sec
sorting block 25, #reads = 1075227 mem = 536880318 peak = 807546880
[M::process] read 695804 sequences (100000044 bp) in 2.780 CPU sec, 2.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283464, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 349, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3117)
[M::mem_pestat] mean and std.dev: (617.08, 571.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.30, 138.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 571, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (697.94, 444.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 640, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3385)
[M::mem_pestat] mean and std.dev: (800.45, 765.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696316 sequences (100000251 bp) in 2.548 CPU sec, 2.753 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283580, 17, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 357, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3374)
[M::mem_pestat] mean and std.dev: (723.94, 696.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.36, 138.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 582, 2164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6256)
[M::mem_pestat] mean and std.dev: (668.60, 794.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 335, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (512.66, 493.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696300 reads in 199.081 CPU sec, 6.404 real sec
[M::mem_process_seqs] Processed 695804 reads in 127.646 CPU sec, 4.046 real sec
sorting block 26, #reads = 1076399 mem = 536879752 peak = 807546880
[M::process] read 696008 sequences (100000033 bp) in 2.760 CPU sec, 2.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283921, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 232, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (408.74, 497.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.41, 138.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 499, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1979)
[M::mem_pestat] mean and std.dev: (615.15, 377.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 376, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (390.38, 258.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696202 sequences (100000065 bp) in 2.623 CPU sec, 2.846 real sec...
sorting block 27, #reads = 1077120 mem = 536878228 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283318, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 298, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (216.27, 105.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.58, 139.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 554, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379)
[M::mem_pestat] mean and std.dev: (1124.24, 1211.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 392, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (497.67, 509.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696316 reads in 194.069 CPU sec, 6.222 real sec
[M::mem_process_seqs] Processed 696008 reads in 131.134 CPU sec, 4.163 real sec
[M::process] read 695530 sequences (100000160 bp) in 2.799 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283812, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 383, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (435.85, 249.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.45, 140.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 472, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (572.86, 557.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 797, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (1005.34, 901.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1076892 mem = 536887406 peak = 807546880
[M::process] read 695512 sequences (100000217 bp) in 3.450 CPU sec, 3.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283236, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 470, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (400.92, 256.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.49, 141.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1158, 1158, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (80, 2775)
[M::mem_pestat] mean and std.dev: (1374.56, 505.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 402, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (394.65, 255.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696202 reads in 200.914 CPU sec, 6.440 real sec
[M::mem_process_seqs] Processed 695530 reads in 134.208 CPU sec, 4.259 real sec
[M::process] read 694920 sequences (100000129 bp) in 2.661 CPU sec, 2.850 real sec...
sorting block 29, #reads = 1075135 mem = 536876969 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283199, 20, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 294, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (586.41, 692.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.46, 138.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 775, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4107)
[M::mem_pestat] mean and std.dev: (861.16, 796.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 285, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (449.67, 434.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694622 sequences (100000086 bp) in 3.250 CPU sec, 3.488 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282807, 28, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 370, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (614.84, 503.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.52, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 407, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3369)
[M::mem_pestat] mean and std.dev: (439.42, 458.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 392, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (498.28, 371.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695512 reads in 202.236 CPU sec, 6.483 real sec
[M::mem_process_seqs] Processed 694920 reads in 136.024 CPU sec, 4.323 real sec
[M::process] read 694744 sequences (100000101 bp) in 2.235 CPU sec, 2.328 real sec...
sorting block 30, #reads = 1075945 mem = 536881309 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283084, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 358, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (514.74, 391.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.14, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 519, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (505.81, 299.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 400, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (461.47, 340.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699260 sequences (100000086 bp) in 3.483 CPU sec, 3.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282999, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 387, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (440.19, 420.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (281.71, 143.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 739, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (797.91, 757.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 331, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (471.05, 349.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694622 reads in 204.943 CPU sec, 6.555 real sec
sorting block 31, #reads = 1075015 mem = 536879258 peak = 807546880
[M::mem_process_seqs] Processed 694744 reads in 136.521 CPU sec, 4.324 real sec
[M::process] read 700266 sequences (100000047 bp) in 2.929 CPU sec, 3.114 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284202, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 246, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (303.37, 209.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.76, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1388, 2777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7831)
[M::mem_pestat] mean and std.dev: (1575.05, 1446.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (333, 361, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (623.40, 512.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1075183 mem = 536881171 peak = 807546880
[M::process] read 699010 sequences (100000105 bp) in 3.426 CPU sec, 3.695 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284449, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 333, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (603.94, 582.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.59, 133.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 597, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (519.33, 292.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 273, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (441.26, 400.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699260 reads in 210.116 CPU sec, 6.731 real sec
[M::mem_process_seqs] Processed 700266 reads in 139.929 CPU sec, 4.428 real sec
[M::process] read 698570 sequences (100000020 bp) in 3.194 CPU sec, 3.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284324, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 354, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (445.12, 408.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (265.41, 133.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 695, 1783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5291)
[M::mem_pestat] mean and std.dev: (759.00, 898.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 477, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (668.50, 540.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1075376 mem = 536881113 peak = 807546880
[M::process] read 697514 sequences (100000301 bp) in 3.085 CPU sec, 3.310 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284183, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 532, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (778.11, 804.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.30, 136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 1031, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4421)
[M::mem_pestat] mean and std.dev: (1024.96, 850.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 423, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (537.44, 462.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699010 reads in 206.233 CPU sec, 6.626 real sec
[M::mem_process_seqs] Processed 698570 reads in 138.819 CPU sec, 4.401 real sec
[M::process] read 697402 sequences (100000012 bp) in 2.869 CPU sec, 3.048 real sec...
sorting block 34, #reads = 1079019 mem = 536880946 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283774, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (333.30, 170.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (270.10, 136.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 589, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (691.00, 590.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 283, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3657)
[M::mem_pestat] mean and std.dev: (680.69, 829.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696776 sequences (100000010 bp) in 3.567 CPU sec, 3.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283977, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 362, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5752)
[M::mem_pestat] mean and std.dev: (821.00, 996.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.93, 137.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (766, 1089, 2704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6580)
[M::mem_pestat] mean and std.dev: (1379.79, 1174.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 200, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (348.70, 314.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697514 reads in 204.197 CPU sec, 6.542 real sec
[M::mem_process_seqs] Processed 697402 reads in 136.735 CPU sec, 4.335 real sec
sorting block 35, #reads = 1078114 mem = 536880230 peak = 807546880
[M::process] read 696688 sequences (100000038 bp) in 2.794 CPU sec, 2.944 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283497, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 331, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (347.32, 264.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (272.59, 137.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 1442, 3190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8560)
[M::mem_pestat] mean and std.dev: (2066.65, 2357.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 275, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (374.04, 235.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1077385 mem = 536877255 peak = 807546880
[M::process] read 696186 sequences (100000024 bp) in 3.283 CPU sec, 3.553 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283929, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 381, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (439.81, 266.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.10, 139.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 624, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3269)
[M::mem_pestat] mean and std.dev: (774.53, 596.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 349, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (534.86, 507.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696776 reads in 205.014 CPU sec, 6.561 real sec
[M::mem_process_seqs] Processed 696688 reads in 137.532 CPU sec, 4.353 real sec
[M::process] read 695858 sequences (100000067 bp) in 2.262 CPU sec, 2.359 real sec...
sorting block 37, #reads = 1077261 mem = 536879493 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283167, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 239, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (238.22, 101.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.45, 140.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 526, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (548.23, 401.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 399, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1327)
[M::mem_pestat] mean and std.dev: (374.75, 176.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695570 sequences (100000273 bp) in 3.207 CPU sec, 3.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283577, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 467, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (495.10, 385.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.31, 140.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 840, 2010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5564)
[M::mem_pestat] mean and std.dev: (891.95, 769.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 385, 2302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6442)
[M::mem_pestat] mean and std.dev: (907.53, 1015.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696186 reads in 202.752 CPU sec, 6.488 real sec
[M::mem_process_seqs] Processed 695858 reads in 132.105 CPU sec, 4.189 real sec
[M::process] read 695612 sequences (100000074 bp) in 2.731 CPU sec, 2.872 real sec...
sorting block 38, #reads = 1076037 mem = 536880503 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283266, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 370, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (649.07, 672.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.75, 140.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 338, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (303.16, 252.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 498, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (532.82, 402.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282963, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 386, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (592.44, 602.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.73, 141.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 974, 3946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10800)
[M::mem_pestat] mean and std.dev: (2438.89, 2736.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 357, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4116)
[M::mem_pestat] mean and std.dev: (908.57, 1023.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695720 sequences (100000197 bp) in 4.063 CPU sec, 4.373 real sec...
[M::mem_process_seqs] Processed 695570 reads in 203.755 CPU sec, 6.541 real sec
[M::mem_process_seqs] Processed 695612 reads in 137.599 CPU sec, 4.368 real sec
sorting block 39, #reads = 1077353 mem = 536882156 peak = 807546880
[M::process] read 695736 sequences (100000208 bp) in 3.336 CPU sec, 3.581 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282883, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 287, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (382.16, 235.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.40, 140.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 708, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3476)
[M::mem_pestat] mean and std.dev: (711.46, 523.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 349, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (314.97, 173.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283209, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 531, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (501.00, 339.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.45, 139.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 794, 1737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191)
[M::mem_pestat] mean and std.dev: (872.89, 611.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 379, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4909)
[M::mem_pestat] mean and std.dev: (1009.37, 1131.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1076084 mem = 536880831 peak = 807546880
[M::process] read 695946 sequences (100000192 bp) in 3.776 CPU sec, 4.162 real sec...
[M::mem_process_seqs] Processed 695720 reads in 203.811 CPU sec, 6.547 real sec
[M::mem_process_seqs] Processed 695736 reads in 137.483 CPU sec, 4.382 real sec
[M::process] read 695564 sequences (100000038 bp) in 3.132 CPU sec, 3.360 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283218, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 584, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (685.95, 633.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (274.03, 139.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 628, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5880)
[M::mem_pestat] mean and std.dev: (1061.71, 1070.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 344, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (336.21, 211.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1075202 mem = 536878266 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283290, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 355, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (521.65, 427.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.74, 139.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 456, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3988)
[M::mem_pestat] mean and std.dev: (731.00, 801.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 321, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (411.68, 360.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695802 sequences (100000036 bp) in 3.502 CPU sec, 3.821 real sec...
[M::mem_process_seqs] Processed 695946 reads in 217.497 CPU sec, 7.042 real sec
[M::mem_process_seqs] Processed 695564 reads in 139.492 CPU sec, 4.500 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282909, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 316, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (359.43, 238.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.87, 138.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 2182, 2505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6815)
[M::mem_pestat] mean and std.dev: (1530.05, 1130.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 306, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (391.96, 287.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695802 reads in 114.229 CPU sec, 3.808 real sec
sorting block 42, #reads = 1074840 mem = 536886742 peak = 807546880
[M::process] read 695696 sequences (100000087 bp) in 4.171 CPU sec, 4.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283260, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 309, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (384.84, 331.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.26, 140.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (559, 1063, 3200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8482)
[M::mem_pestat] mean and std.dev: (1517.74, 1287.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 402, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (501.78, 382.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695772 sequences (100000253 bp) in 3.319 CPU sec, 3.627 real sec...
[M::mem_process_seqs] Processed 695696 reads in 117.471 CPU sec, 3.908 real sec
sorting block 43, #reads = 1076249 mem = 536882194 peak = 807546880
[M::process] read 695372 sequences (100000026 bp) in 3.086 CPU sec, 3.334 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282852, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 465, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (405.05, 243.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.18, 139.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 763, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4463)
[M::mem_pestat] mean and std.dev: (1028.15, 921.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 237, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (216.17, 52.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695772 reads in 120.006 CPU sec, 4.067 real sec
[M::process] read 695470 sequences (100000119 bp) in 3.151 CPU sec, 3.382 real sec...
sorting block 44, #reads = 1076001 mem = 536879708 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283014, 17, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 443, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4057)
[M::mem_pestat] mean and std.dev: (820.21, 847.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.64, 139.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 807, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (926.82, 700.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 346, 2481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6965)
[M::mem_pestat] mean and std.dev: (906.50, 1308.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695028 sequences (100000089 bp) in 3.110 CPU sec, 3.342 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283497, 29, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 1116, 2208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6288)
[M::mem_pestat] mean and std.dev: (1239.63, 967.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.38, 140.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 746, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (1014.41, 841.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 274, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (296.00, 192.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695372 reads in 210.839 CPU sec, 6.785 real sec
[M::mem_process_seqs] Processed 695470 reads in 142.492 CPU sec, 4.537 real sec
sorting block 45, #reads = 1075885 mem = 536879655 peak = 807546880
[M::process] read 694500 sequences (100000193 bp) in 3.185 CPU sec, 3.398 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283043, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 473, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (793.22, 658.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.04, 141.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 246, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (783.20, 1048.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 358, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (392.79, 291.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282506, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 679, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3688)
[M::mem_pestat] mean and std.dev: (783.12, 718.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.98, 141.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 996, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635)
[M::mem_pestat] mean and std.dev: (833.58, 572.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (472, 630, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (682.10, 400.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694448 sequences (100000163 bp) in 3.122 CPU sec, 3.400 real sec...
[M::mem_process_seqs] Processed 695028 reads in 206.928 CPU sec, 6.661 real sec
sorting block 46, #reads = 1075377 mem = 536879541 peak = 807546880
[M::mem_process_seqs] Processed 694500 reads in 139.252 CPU sec, 4.429 real sec
[M::process] read 693910 sequences (100000140 bp) in 3.236 CPU sec, 3.485 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282665, 35, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 388, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4036)
[M::mem_pestat] mean and std.dev: (739.85, 784.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (280.83, 142.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 851, 2531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6919)
[M::mem_pestat] mean and std.dev: (1191.44, 1262.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 375, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (439.82, 291.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1075862 mem = 536877427 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282282, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 312, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (496.22, 373.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (280.83, 141.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 723, 2572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6834)
[M::mem_pestat] mean and std.dev: (1881.14, 2153.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 355, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (557.40, 475.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696318 sequences (100000112 bp) in 3.048 CPU sec, 3.293 real sec...
[M::mem_process_seqs] Processed 694448 reads in 206.077 CPU sec, 6.638 real sec
[M::mem_process_seqs] Processed 693910 reads in 139.270 CPU sec, 4.426 real sec
[M::process] read 700424 sequences (100000249 bp) in 3.247 CPU sec, 3.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283368, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 428, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (361.07, 183.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.50, 140.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 1007, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (859.56, 494.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 336, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (512.69, 437.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1074747 mem = 536876664 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285520, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 337, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (438.65, 340.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.32, 134.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 881, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (797.67, 712.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 432, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (389.88, 236.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699902 sequences (100000197 bp) in 3.389 CPU sec, 3.682 real sec...
[M::mem_process_seqs] Processed 696318 reads in 206.947 CPU sec, 6.658 real sec
[M::mem_process_seqs] Processed 700424 reads in 138.897 CPU sec, 4.411 real sec
sorting block 49, #reads = 1074310 mem = 536880738 peak = 807546880
[M::process] read 699166 sequences (100000265 bp) in 3.714 CPU sec, 4.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284969, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 307, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (567.27, 573.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.35, 135.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 912, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (918.58, 733.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 398, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (335.75, 192.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699902 reads in 116.008 CPU sec, 3.851 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284046, 23, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 215, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (279.41, 175.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.84, 137.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 765, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4474)
[M::mem_pestat] mean and std.dev: (1043.13, 862.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 542, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (562.16, 430.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698666 sequences (100000247 bp) in 3.353 CPU sec, 3.626 real sec...
[M::mem_process_seqs] Processed 699166 reads in 115.428 CPU sec, 3.826 real sec
sorting block 50, #reads = 1080233 mem = 536879676 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284357, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (422.19, 366.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.30, 138.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 833, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4523)
[M::mem_pestat] mean and std.dev: (1078.35, 999.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 322, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3199)
[M::mem_pestat] mean and std.dev: (568.93, 457.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698446 sequences (100000166 bp) in 3.458 CPU sec, 3.791 real sec...
[M::mem_process_seqs] Processed 698666 reads in 112.982 CPU sec, 3.761 real sec
sorting block 51, #reads = 1079691 mem = 536883739 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283721, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 447, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (578.37, 551.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.65, 138.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 668, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (699.36, 463.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 320, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (492.00, 458.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697540 sequences (100000008 bp) in 3.339 CPU sec, 3.563 real sec...
[M::mem_process_seqs] Processed 698446 reads in 114.920 CPU sec, 3.842 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283465, 34, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 283, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (276.44, 216.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.72, 140.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 1883, 2187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5473)
[M::mem_pestat] mean and std.dev: (1331.67, 1184.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 376, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4106)
[M::mem_pestat] mean and std.dev: (752.08, 777.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697466 sequences (100000045 bp) in 3.106 CPU sec, 3.364 real sec...
[M::mem_process_seqs] Processed 697540 reads in 115.626 CPU sec, 3.829 real sec
sorting block 52, #reads = 1080334 mem = 536878956 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283322, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (380.68, 267.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.52, 139.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (41, 336, 2692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7994)
[M::mem_pestat] mean and std.dev: (1317.16, 1875.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 471, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (563.41, 411.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697034 sequences (100000259 bp) in 3.406 CPU sec, 3.681 real sec...
[M::mem_process_seqs] Processed 697466 reads in 116.134 CPU sec, 3.852 real sec
sorting block 53, #reads = 1078242 mem = 536878033 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283447, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 302, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (326.86, 219.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.87, 140.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 336, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5233)
[M::mem_pestat] mean and std.dev: (603.54, 716.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 352, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (385.72, 269.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697920 sequences (100000006 bp) in 3.726 CPU sec, 4.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283545, 24, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 273, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (415.64, 412.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.73, 138.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 747, 1892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4874)
[M::mem_pestat] mean and std.dev: (1077.78, 916.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 761, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (862.88, 808.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696382 sequences (100000211 bp) in 3.232 CPU sec, 3.460 real sec...
[M::mem_process_seqs] Processed 697920 reads in 116.461 CPU sec, 3.746 real sec
sorting block 54, #reads = 1078103 mem = 536879974 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283435, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 306, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (626.43, 661.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.70, 140.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 490, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (679.38, 471.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 320, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (413.96, 366.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695972 sequences (100000219 bp) in 3.536 CPU sec, 3.798 real sec...
[M::mem_process_seqs] Processed 697034 reads in 344.604 CPU sec, 11.203 real sec
[M::mem_process_seqs] Processed 696382 reads in 115.170 CPU sec, 3.714 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283277, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 293, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (370.42, 239.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.14, 140.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 523, 2546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7062)
[M::mem_pestat] mean and std.dev: (1188.79, 1202.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 385, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (601.93, 678.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696180 sequences (100000074 bp) in 3.290 CPU sec, 3.785 real sec...
sorting block 55, #reads = 1078242 mem = 536879191 peak = 807546880
[M::mem_process_seqs] Processed 695972 reads in 115.282 CPU sec, 4.006 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283599, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 472, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (766.43, 692.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.92, 140.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 787, 2746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7874)
[M::mem_pestat] mean and std.dev: (1353.04, 1492.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (347, 772, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (772.72, 583.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695934 sequences (100000267 bp) in 3.579 CPU sec, 3.896 real sec...
[M::mem_process_seqs] Processed 696180 reads in 115.261 CPU sec, 4.323 real sec
sorting block 56, #reads = 1077243 mem = 536877610 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282841, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 234, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (515.27, 571.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.57, 139.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 786, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4225)
[M::mem_pestat] mean and std.dev: (822.78, 765.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 421, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (525.52, 501.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696014 sequences (100000225 bp) in 3.511 CPU sec, 4.138 real sec...
[M::mem_process_seqs] Processed 695934 reads in 118.146 CPU sec, 4.616 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283293, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 449, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (522.82, 334.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.70, 140.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (753, 1103, 2698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6588)
[M::mem_pestat] mean and std.dev: (1646.33, 1664.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 353, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (397.93, 251.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695998 sequences (100000056 bp) in 3.456 CPU sec, 3.739 real sec...
[M::mem_process_seqs] Processed 696014 reads in 115.112 CPU sec, 3.830 real sec
sorting block 57, #reads = 1076851 mem = 536880360 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283407, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 174, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (249.08, 177.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.46, 140.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (753, 1467, 3485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8949)
[M::mem_pestat] mean and std.dev: (2158.04, 1558.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 493, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3676)
[M::mem_pestat] mean and std.dev: (828.72, 763.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695920 sequences (100000054 bp) in 3.692 CPU sec, 4.040 real sec...
[M::mem_process_seqs] Processed 695998 reads in 115.834 CPU sec, 4.389 real sec
sorting block 58, #reads = 1075198 mem = 536886636 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282719, 9, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 272, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (617.55, 714.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.73, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 339, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (314.45, 196.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695920 reads in 115.011 CPU sec, 3.844 real sec
[M::process] read 695760 sequences (100000135 bp) in 3.786 CPU sec, 4.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283091, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 375, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (312.52, 161.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.45, 139.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 399, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (758.04, 759.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (342, 675, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (730.06, 414.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695760 reads in 115.359 CPU sec, 3.837 real sec
[M::process] read 695640 sequences (100000003 bp) in 4.458 CPU sec, 4.902 real sec...
sorting block 59, #reads = 1076113 mem = 536880022 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282818, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 443, 2916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8232)
[M::mem_pestat] mean and std.dev: (1573.36, 2116.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (274.74, 138.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 370, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (370.39, 296.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 467, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (615.93, 526.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695296 sequences (100000084 bp) in 3.512 CPU sec, 3.809 real sec...
[M::mem_process_seqs] Processed 695640 reads in 117.039 CPU sec, 4.466 real sec
sorting block 60, #reads = 1075646 mem = 536880424 peak = 807546880
[M::process] read 695212 sequences (100000151 bp) in 2.788 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283711, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 434, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (595.00, 468.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.48, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 552, 3814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10934)
[M::mem_pestat] mean and std.dev: (1609.06, 1857.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 420, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406)
[M::mem_pestat] mean and std.dev: (766.39, 863.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695296 reads in 116.230 CPU sec, 3.909 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283331, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 319, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (334.67, 170.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.61, 138.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 681, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (693.50, 580.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 328, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (408.57, 304.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695212 reads in 112.273 CPU sec, 3.758 real sec
[M::process] read 695122 sequences (100000292 bp) in 3.893 CPU sec, 4.348 real sec...
sorting block 61, #reads = 1076005 mem = 536879527 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283262, 42, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (397.29, 329.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.85, 137.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1002, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3745)
[M::mem_pestat] mean and std.dev: (836.18, 663.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (318, 433, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (616.50, 446.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695122 reads in 114.235 CPU sec, 4.027 real sec
[M::process] read 695074 sequences (100000058 bp) in 4.382 CPU sec, 4.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283200, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 693, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (798.44, 732.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (276.00, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (713, 874, 3491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9047)
[M::mem_pestat] mean and std.dev: (1752.91, 1385.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 389, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3736)
[M::mem_pestat] mean and std.dev: (727.53, 694.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1076551 mem = 536878349 peak = 807546880
[M::mem_process_seqs] Processed 695074 reads in 111.680 CPU sec, 3.732 real sec
[M::process] read 694552 sequences (100000055 bp) in 4.136 CPU sec, 4.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282823, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 509, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (425.83, 247.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (278.21, 139.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 716, 2483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6993)
[M::mem_pestat] mean and std.dev: (1278.33, 1521.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 337, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (523.97, 425.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694264 sequences (100000186 bp) in 3.738 CPU sec, 4.085 real sec...
[M::mem_process_seqs] Processed 694552 reads in 115.217 CPU sec, 4.161 real sec
sorting block 63, #reads = 1075190 mem = 536879465 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 283089, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 859, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3633)
[M::mem_pestat] mean and std.dev: (829.00, 732.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (280.13, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 305, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (666.53, 617.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 443, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (727.47, 552.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694264 reads in 110.882 CPU sec, 3.738 real sec
[M::process] read 694504 sequences (100000172 bp) in 3.895 CPU sec, 4.260 real sec...
sorting block 64, #reads = 1075112 mem = 536879189 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282428, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 269, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (399.22, 358.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (280.65, 142.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 516, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3858)
[M::mem_pestat] mean and std.dev: (647.94, 733.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 402, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (375.66, 157.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704572 sequences (100000000 bp) in 3.320 CPU sec, 3.534 real sec...
[M::mem_process_seqs] Processed 694504 reads in 118.164 CPU sec, 3.969 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 286059, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 321, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (442.79, 453.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.84, 129.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 898, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4970)
[M::mem_pestat] mean and std.dev: (1045.43, 1047.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 316, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (428.21, 351.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704572 reads in 122.246 CPU sec, 4.053 real sec
[M::process] read 702446 sequences (100000042 bp) in 4.304 CPU sec, 4.749 real sec...
sorting block 65, #reads = 1075514 mem = 536883955 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 285883, 31, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 285, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (312.62, 189.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (256.89, 133.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 1060, 2724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7650)
[M::mem_pestat] mean and std.dev: (1515.14, 1874.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 368, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4371)
[M::mem_pestat] mean and std.dev: (862.19, 1028.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702446 reads in 114.452 CPU sec, 4.023 real sec
[M::process] read 700872 sequences (100000157 bp) in 4.257 CPU sec, 4.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285646, 32, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 275, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (273.69, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (260.71, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 898, 2222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5938)
[M::mem_pestat] mean and std.dev: (1190.62, 1115.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 366, 2795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8009)
[M::mem_pestat] mean and std.dev: (1454.48, 1952.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1074595 mem = 536879006 peak = 807546880
[M::mem_process_seqs] Processed 700872 reads in 110.407 CPU sec, 3.885 real sec
[M::process] read 700664 sequences (100000213 bp) in 4.340 CPU sec, 4.809 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285184, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 363, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1766)
[M::mem_pestat] mean and std.dev: (376.88, 282.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (262.29, 135.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 567, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (648.35, 622.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 411, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (463.56, 231.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700664 reads in 113.992 CPU sec, 3.986 real sec
[M::process] read 699664 sequences (100000282 bp) in 4.169 CPU sec, 4.613 real sec...
sorting block 67, #reads = 1079462 mem = 536881971 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 285147, 37, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 750, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (744.23, 626.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (266.73, 138.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 1002, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3944)
[M::mem_pestat] mean and std.dev: (1062.00, 864.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 360, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (375.76, 287.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699222 sequences (100000188 bp) in 3.816 CPU sec, 4.167 real sec...
[M::mem_process_seqs] Processed 699664 reads in 118.769 CPU sec, 4.212 real sec
sorting block 68, #reads = 1078486 mem = 536880024 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285329, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 539, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (646.80, 583.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.11, 139.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 579, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4658)
[M::mem_pestat] mean and std.dev: (1150.42, 1222.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 329, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (550.39, 494.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698618 sequences (100000031 bp) in 3.437 CPU sec, 3.732 real sec...
[M::mem_process_seqs] Processed 699222 reads in 126.661 CPU sec, 4.207 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284774, 28, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 709, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5022)
[M::mem_pestat] mean and std.dev: (879.47, 800.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.69, 141.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 460, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6290)
[M::mem_pestat] mean and std.dev: (912.08, 1180.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 383, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (476.95, 366.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698096 sequences (100000139 bp) in 3.883 CPU sec, 4.319 real sec...
[M::mem_process_seqs] Processed 698618 reads in 115.794 CPU sec, 4.126 real sec
sorting block 69, #reads = 1075316 mem = 536877957 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285002, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 399, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (617.34, 543.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.16, 141.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 753, 2157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5537)
[M::mem_pestat] mean and std.dev: (1009.38, 737.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 362, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (364.78, 155.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698096 reads in 116.308 CPU sec, 3.884 real sec
[M::process] read 697784 sequences (100000167 bp) in 4.383 CPU sec, 4.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284046, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 314, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (451.49, 385.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.94, 142.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 366, 4110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11698)
[M::mem_pestat] mean and std.dev: (1479.33, 1948.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 433, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819)
[M::mem_pestat] mean and std.dev: (626.05, 727.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1077059 mem = 536879816 peak = 807546880
[M::mem_process_seqs] Processed 697784 reads in 120.451 CPU sec, 4.003 real sec
[M::process] read 697562 sequences (100000108 bp) in 4.406 CPU sec, 4.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283805, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 355, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (327.84, 143.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.98, 142.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 354, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (429.50, 417.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 387, 2131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5877)
[M::mem_pestat] mean and std.dev: (937.27, 999.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697562 reads in 119.036 CPU sec, 4.124 real sec
[M::process] read 697000 sequences (100000192 bp) in 4.144 CPU sec, 4.633 real sec...
sorting block 71, #reads = 1077105 mem = 536878662 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283462, 30, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (414.44, 317.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (275.11, 143.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 376, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (334.56, 199.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 337, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (375.17, 218.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696718 sequences (100000299 bp) in 3.600 CPU sec, 3.958 real sec...
[M::mem_process_seqs] Processed 697000 reads in 119.231 CPU sec, 4.175 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283262, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 333, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (354.25, 211.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (275.42, 142.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 891, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4021)
[M::mem_pestat] mean and std.dev: (846.19, 738.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 383, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (482.69, 360.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1075323 mem = 536877750 peak = 807546880
[M::mem_process_seqs] Processed 696718 reads in 117.119 CPU sec, 3.973 real sec
[M::process] read 696638 sequences (100000238 bp) in 4.281 CPU sec, 4.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283412, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 399, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (462.32, 347.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.69, 141.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 468, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (406.53, 328.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 908, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5624)
[M::mem_pestat] mean and std.dev: (1292.30, 1316.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696624 sequences (100000229 bp) in 3.592 CPU sec, 4.227 real sec...
[M::mem_process_seqs] Processed 696638 reads in 121.161 CPU sec, 4.530 real sec
sorting block 73, #reads = 1073372 mem = 536880351 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283648, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (549.26, 632.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.95, 141.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 1274, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (1225.38, 1049.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 535, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (483.69, 309.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696556 sequences (100000167 bp) in 3.409 CPU sec, 3.739 real sec...
[M::mem_process_seqs] Processed 696624 reads in 120.633 CPU sec, 4.026 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283087, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 238, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (256.22, 176.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.73, 140.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 752, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (614.47, 514.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 373, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (344.39, 171.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1073403 mem = 536879510 peak = 807546880
[M::mem_process_seqs] Processed 696556 reads in 118.427 CPU sec, 4.094 real sec
[M::process] read 697076 sequences (100000287 bp) in 4.078 CPU sec, 4.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284067, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 294, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (342.00, 242.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.66, 141.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 1340, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5104)
[M::mem_pestat] mean and std.dev: (769.29, 653.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 379, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (627.94, 621.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695916 sequences (100000134 bp) in 3.714 CPU sec, 4.028 real sec...
[M::mem_process_seqs] Processed 697076 reads in 120.252 CPU sec, 4.211 real sec
sorting block 75, #reads = 1073574 mem = 536880988 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282765, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 354, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (473.40, 396.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (276.24, 141.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 734, 2216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5800)
[M::mem_pestat] mean and std.dev: (989.70, 1130.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 694, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3833)
[M::mem_pestat] mean and std.dev: (717.71, 620.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695916 reads in 123.514 CPU sec, 4.155 real sec
[M::process] read 696134 sequences (100000235 bp) in 4.436 CPU sec, 4.886 real sec...
sorting block 76, #reads = 1073689 mem = 536879711 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283340, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 485, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (500.28, 276.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.71, 139.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 477, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (641.30, 763.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 354, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (421.70, 306.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696134 reads in 118.247 CPU sec, 4.058 real sec
[M::process] read 696360 sequences (100000184 bp) in 3.876 CPU sec, 4.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283495, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 507, 2036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5636)
[M::mem_pestat] mean and std.dev: (888.06, 873.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.94, 138.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 314, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (487.07, 467.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 423, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (460.89, 309.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696360 reads in 115.676 CPU sec, 3.842 real sec
[M::process] read 696318 sequences (100000114 bp) in 4.869 CPU sec, 5.356 real sec...
sorting block 77, #reads = 1071803 mem = 536880010 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283221, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 274, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (344.72, 225.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.99, 136.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 592, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (609.04, 621.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 576, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (469.81, 257.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696318 reads in 119.099 CPU sec, 4.083 real sec
[M::process] read 696368 sequences (100000006 bp) in 3.778 CPU sec, 4.220 real sec...
sorting block 78, #reads = 1072602 mem = 536878536 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282894, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 438, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (557.94, 456.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.74, 138.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 359, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (582.29, 521.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 369, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (340.23, 183.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696684 sequences (100000064 bp) in 3.266 CPU sec, 3.593 real sec...
[M::mem_process_seqs] Processed 696368 reads in 119.423 CPU sec, 4.098 real sec
[M::process] read 696862 sequences (100000220 bp) in 3.202 CPU sec, 3.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283703, 32, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 340, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (462.13, 385.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.87, 139.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 606, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (658.79, 496.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 399, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3578)
[M::mem_pestat] mean and std.dev: (736.87, 737.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1071883 mem = 536877674 peak = 807546880
[M::process] read 703404 sequences (100000064 bp) in 2.920 CPU sec, 3.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283793, 28, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 499, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (688.12, 572.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.17, 141.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 654, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (815.14, 678.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 284, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (454.00, 397.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696684 reads in 223.610 CPU sec, 7.165 real sec
[M::mem_process_seqs] Processed 696862 reads in 153.884 CPU sec, 4.911 real sec
[M::process] read 704036 sequences (100000111 bp) in 2.765 CPU sec, 2.919 real sec...
sorting block 80, #reads = 1073715 mem = 536883777 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285999, 29, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 324, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (639.27, 648.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (251.28, 128.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 839, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (864.10, 718.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (498.69, 503.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702508 sequences (100000199 bp) in 3.914 CPU sec, 4.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286275, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 354, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (524.90, 494.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (250.50, 127.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 576, 2447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6943)
[M::mem_pestat] mean and std.dev: (939.50, 933.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 374, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (488.13, 414.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703404 reads in 237.745 CPU sec, 7.627 real sec
[M::mem_process_seqs] Processed 704036 reads in 158.272 CPU sec, 5.060 real sec
[M::process] read 701626 sequences (100000048 bp) in 2.525 CPU sec, 2.610 real sec...
sorting block 81, #reads = 1072446 mem = 536881034 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286101, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 360, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (384.61, 231.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (255.51, 130.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 573, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (626.07, 627.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 341, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (597.20, 545.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701784 sequences (100000157 bp) in 3.189 CPU sec, 3.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285951, 20, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 202, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (219.23, 103.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (258.00, 132.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 419, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (602.42, 739.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 602, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (758.62, 620.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701834 sequences (100000213 bp) in 1.894 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 702508 reads in 234.581 CPU sec, 7.746 real sec
sorting block 82, #reads = 1075526 mem = 536882270 peak = 807546880
[M::mem_process_seqs] Processed 701626 reads in 149.529 CPU sec, 4.763 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286196, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 385, 4070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11754)
[M::mem_pestat] mean and std.dev: (1712.95, 2286.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (257.93, 132.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 1238, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4866)
[M::mem_pestat] mean and std.dev: (1133.33, 769.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 297, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (298.69, 154.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1075845 mem = 536880580 peak = 807546880
[M::process] read 700164 sequences (100000187 bp) in 3.820 CPU sec, 4.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285965, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 451, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (595.32, 603.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (257.23, 132.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 969, 2668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7380)
[M::mem_pestat] mean and std.dev: (1270.62, 1005.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 617, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (507.92, 301.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701784 reads in 230.619 CPU sec, 7.380 real sec
[M::process] read 699712 sequences (100000278 bp) in 2.482 CPU sec, 2.551 real sec...
[M::mem_process_seqs] Processed 701834 reads in 156.485 CPU sec, 5.304 real sec
sorting block 84, #reads = 1075052 mem = 536889694 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 286057, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 465, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3420)
[M::mem_pestat] mean and std.dev: (602.98, 502.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.58, 136.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 318, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4250)
[M::mem_pestat] mean and std.dev: (691.75, 730.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 259, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (330.80, 180.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699022 sequences (100000186 bp) in 3.285 CPU sec, 3.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285095, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 354, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (341.84, 174.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (266.12, 137.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 938, 2649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7055)
[M::mem_pestat] mean and std.dev: (1619.13, 1821.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 382, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (393.52, 205.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698926 sequences (100000175 bp) in 1.962 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 700164 reads in 226.379 CPU sec, 7.578 real sec
[M::mem_process_seqs] Processed 699712 reads in 148.628 CPU sec, 4.724 real sec
sorting block 85, #reads = 1074299 mem = 536885090 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285415, 25, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 393, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1140)
[M::mem_pestat] mean and std.dev: (328.30, 150.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.34, 137.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 2514, 3578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9566)
[M::mem_pestat] mean and std.dev: (2202.76, 1848.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 321, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4260)
[M::mem_pestat] mean and std.dev: (954.17, 1035.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698110 sequences (100000008 bp) in 3.317 CPU sec, 3.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285157, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 494, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (698.96, 714.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.40, 139.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 536, 2220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6272)
[M::mem_pestat] mean and std.dev: (1038.41, 1054.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 534, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (535.66, 353.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699022 reads in 213.947 CPU sec, 6.813 real sec
[M::process] read 697738 sequences (100000160 bp) in 2.675 CPU sec, 2.726 real sec...
sorting block 86, #reads = 1075471 mem = 536877993 peak = 807546880
[M::mem_process_seqs] Processed 698926 reads in 143.729 CPU sec, 4.864 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283823, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 257, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644)
[M::mem_pestat] mean and std.dev: (681.87, 871.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (271.42, 140.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 788, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (1068.29, 1015.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 489, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4044)
[M::mem_pestat] mean and std.dev: (793.58, 674.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1074621 mem = 536877609 peak = 807546880
[M::process] read 696864 sequences (100000213 bp) in 3.744 CPU sec, 4.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284125, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 274, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (251.63, 111.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.94, 141.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 733, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (637.90, 418.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 338, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (498.67, 421.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698110 reads in 215.084 CPU sec, 7.186 real sec
[M::mem_process_seqs] Processed 697738 reads in 145.463 CPU sec, 4.595 real sec
[M::process] read 697308 sequences (100000254 bp) in 2.970 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283681, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (319.25, 226.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.49, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 568, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127)
[M::mem_pestat] mean and std.dev: (802.21, 750.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5429)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 429, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (681.09, 515.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 88, #reads = 1073391 mem = 536879679 peak = 807546880
[M::process] read 696580 sequences (100000119 bp) in 3.592 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283922, 42, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 599, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (717.68, 662.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.56, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (676, 902, 2537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6259)
[M::mem_pestat] mean and std.dev: (1400.92, 1361.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5133)
[M::mem_pestat] mean and std.dev: (937.12, 1110.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696864 reads in 215.974 CPU sec, 6.905 real sec
[M::mem_process_seqs] Processed 697308 reads in 145.223 CPU sec, 4.590 real sec
[M::process] read 696292 sequences (100000100 bp) in 3.419 CPU sec, 3.673 real sec...
sorting block 89, #reads = 1072408 mem = 536878515 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283382, 36, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 417, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (731.33, 747.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.59, 141.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 826, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (651.50, 444.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 590, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (656.54, 661.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283004, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 470, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (604.87, 480.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (275.06, 141.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 378, 2265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6159)
[M::mem_pestat] mean and std.dev: (731.13, 788.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 341, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (570.66, 683.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696812 sequences (100000066 bp) in 3.875 CPU sec, 4.220 real sec...
[M::mem_process_seqs] Processed 696580 reads in 212.559 CPU sec, 6.816 real sec
[M::mem_process_seqs] Processed 696292 reads in 143.990 CPU sec, 4.561 real sec
sorting block 90, #reads = 1073418 mem = 536879135 peak = 807546880
[M::process] read 696432 sequences (100000025 bp) in 3.545 CPU sec, 3.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283769, 35, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 315, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (592.35, 607.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (275.14, 142.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 1359, 2982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8172)
[M::mem_pestat] mean and std.dev: (1518.47, 1302.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 443, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (690.36, 622.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283366, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 361, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (540.88, 441.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.82, 142.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 601, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (592.93, 436.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 764, 2925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8177)
[M::mem_pestat] mean and std.dev: (1619.71, 1839.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1072629 mem = 536881078 peak = 807546880
[M::mem_process_seqs] Processed 696812 reads in 208.875 CPU sec, 6.716 real sec
[M::process] read 696514 sequences (100000130 bp) in 4.043 CPU sec, 4.458 real sec...
[M::mem_process_seqs] Processed 696432 reads in 136.939 CPU sec, 4.367 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283240, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 383, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (500.34, 419.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (276.47, 144.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 980, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (1128.04, 855.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 376, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (489.82, 356.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696384 sequences (100000242 bp) in 3.411 CPU sec, 3.750 real sec...
[M::mem_process_seqs] Processed 696514 reads in 115.500 CPU sec, 3.818 real sec
sorting block 92, #reads = 1073169 mem = 536881917 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283775, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 369, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (644.59, 634.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (277.14, 144.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 864, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4774)
[M::mem_pestat] mean and std.dev: (1097.88, 1011.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (351.50, 240.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696374 sequences (100000263 bp) in 3.842 CPU sec, 4.240 real sec...
[M::mem_process_seqs] Processed 696384 reads in 116.537 CPU sec, 4.020 real sec
sorting block 93, #reads = 1073667 mem = 536879956 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283033, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 412, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3455)
[M::mem_pestat] mean and std.dev: (702.38, 679.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (276.21, 144.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 500, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5825)
[M::mem_pestat] mean and std.dev: (1037.19, 1104.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 446, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (596.56, 554.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699004 sequences (100000107 bp) in 3.084 CPU sec, 3.563 real sec...
[M::mem_process_seqs] Processed 696374 reads in 120.496 CPU sec, 4.192 real sec
[M::process] read 703480 sequences (100000086 bp) in 3.305 CPU sec, 3.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283828, 30, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 356, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (322.88, 163.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (268.68, 141.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 763, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (768.70, 610.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 277, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (377.56, 313.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 94, #reads = 1072712 mem = 536878119 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286208, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 376, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737)
[M::mem_pestat] mean and std.dev: (529.73, 483.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (254.26, 131.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 382, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (690.00, 643.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 319, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (374.29, 289.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699004 reads in 224.522 CPU sec, 7.208 real sec
[M::process] read 701376 sequences (100000193 bp) in 4.299 CPU sec, 4.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285344, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 377, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2362)
[M::mem_pestat] mean and std.dev: (586.92, 548.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (259.05, 133.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 479, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (563.41, 428.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 243, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (680.94, 834.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701376 reads in 105.783 CPU sec, 3.460 real sec
sorting block 95, #reads = 1065300 mem = 536881144 peak = 807546880
[M::process] read 700300 sequences (100000000 bp) in 4.875 CPU sec, 5.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285176, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 506, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (463.00, 218.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.73, 134.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 1058, 1653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (1044.47, 956.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 251, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (395.48, 329.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703480 reads in 344.962 CPU sec, 12.768 real sec
[M::mem_process_seqs] Processed 700300 reads in 107.087 CPU sec, 3.452 real sec
[M::process] read 700180 sequences (100000196 bp) in 4.423 CPU sec, 4.847 real sec...
sorting block 96, #reads = 1077976 mem = 536878739 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285286, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 304, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (295.49, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.33, 135.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 447, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (593.00, 443.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 306, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (365.33, 290.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700180 reads in 113.885 CPU sec, 3.948 real sec
[M::process] read 699598 sequences (100000201 bp) in 4.170 CPU sec, 4.605 real sec...
sorting block 97, #reads = 1079022 mem = 536881700 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285057, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 627, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4493)
[M::mem_pestat] mean and std.dev: (745.95, 683.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.90, 136.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 869, 2417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7009)
[M::mem_pestat] mean and std.dev: (1100.47, 1094.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 324, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (343.97, 209.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699598 reads in 114.286 CPU sec, 3.906 real sec
[M::process] read 699058 sequences (100000036 bp) in 4.150 CPU sec, 4.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285022, 38, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 394, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (586.18, 553.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.43, 137.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 891, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5525)
[M::mem_pestat] mean and std.dev: (1207.68, 1248.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 320, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (365.42, 249.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699058 reads in 111.533 CPU sec, 3.829 real sec
sorting block 98, #reads = 1077499 mem = 536878872 peak = 807546880
[M::process] read 698912 sequences (100000183 bp) in 4.507 CPU sec, 5.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284785, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 452, 1927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5353)
[M::mem_pestat] mean and std.dev: (746.78, 690.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.39, 139.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 686, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (635.95, 613.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (369, 727, 2811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7695)
[M::mem_pestat] mean and std.dev: (1072.11, 996.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698912 reads in 113.600 CPU sec, 3.883 real sec
[M::process] read 698678 sequences (100000273 bp) in 4.212 CPU sec, 4.715 real sec...
sorting block 99, #reads = 1077689 mem = 536878516 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284442, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 602, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (697.06, 579.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (269.09, 139.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 538, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3897)
[M::mem_pestat] mean and std.dev: (864.11, 869.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 224, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (315.65, 176.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698892 sequences (100000230 bp) in 3.664 CPU sec, 4.091 real sec...
[M::process] read 698444 sequences (100000290 bp) in 1.968 CPU sec, 2.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 285032, 26, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 842, 2408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6450)
[M::mem_pestat] mean and std.dev: (1133.58, 949.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.84, 139.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 979, 1962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5052)
[M::mem_pestat] mean and std.dev: (1358.32, 1417.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 244, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (225.33, 67.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697816 sequences (100000087 bp) in 1.950 CPU sec, 1.949 real sec...
[M::mem_process_seqs] Processed 698892 reads in 126.721 CPU sec, 4.173 real sec
sorting block 100, #reads = 1074934 mem = 536880880 peak = 807546880
[M::mem_process_seqs] Processed 698678 reads in 303.391 CPU sec, 10.043 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284685, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 448, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (376.38, 243.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.69, 140.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 335, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (374.95, 215.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (452, 476, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (580.29, 361.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697236 sequences (100000151 bp) in 3.209 CPU sec, 3.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284409, 38, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 313, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (558.33, 598.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.48, 141.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 1007, 2370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6104)
[M::mem_pestat] mean and std.dev: (1441.75, 1305.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 219, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (466.80, 486.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698444 reads in 222.448 CPU sec, 7.076 real sec
sorting block 101, #reads = 1075442 mem = 536880704 peak = 807546880
[M::mem_process_seqs] Processed 697816 reads in 129.924 CPU sec, 4.122 real sec
[M::process] read 696544 sequences (100000115 bp) in 3.598 CPU sec, 3.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283764, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 1096, 3791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10867)
[M::mem_pestat] mean and std.dev: (2035.45, 2500.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.29, 141.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 400, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (359.07, 334.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 459, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (558.31, 515.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1076491 mem = 536879365 peak = 807546880
[M::process] read 696772 sequences (100000151 bp) in 2.987 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283774, 34, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 394, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (833.09, 793.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.86, 142.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1074, 2636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7306)
[M::mem_pestat] mean and std.dev: (1747.82, 1995.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 420, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (675.27, 653.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697236 reads in 211.930 CPU sec, 6.773 real sec
[M::mem_process_seqs] Processed 696544 reads in 142.311 CPU sec, 4.494 real sec
[M::process] read 696326 sequences (100000171 bp) in 3.819 CPU sec, 4.176 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283541, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 324, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (652.23, 636.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.07, 141.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 653, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2472)
[M::mem_pestat] mean and std.dev: (592.04, 485.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (282.07, 104.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696772 reads in 124.253 CPU sec, 4.106 real sec
sorting block 103, #reads = 1074570 mem = 536878568 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283421, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 255, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (524.74, 499.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.80, 141.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 721, 2278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5870)
[M::mem_pestat] mean and std.dev: (1302.06, 1206.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 300, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (450.50, 329.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696456 sequences (100000028 bp) in 3.975 CPU sec, 4.296 real sec...
[M::mem_process_seqs] Processed 696326 reads in 143.355 CPU sec, 4.745 real sec
sorting block 104, #reads = 1073210 mem = 536878602 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283455, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 419, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (477.57, 375.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.63, 140.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 891, 2857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7509)
[M::mem_pestat] mean and std.dev: (1802.11, 2075.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 523, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (593.41, 478.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696584 sequences (100000123 bp) in 4.109 CPU sec, 4.527 real sec...
[M::mem_process_seqs] Processed 696456 reads in 117.850 CPU sec, 4.121 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283322, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 511, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4103)
[M::mem_pestat] mean and std.dev: (927.28, 851.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.51, 141.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 442, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2093)
[M::mem_pestat] mean and std.dev: (475.15, 279.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 265, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (375.73, 269.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 105, #reads = 1073201 mem = 536877335 peak = 807546880
[M::mem_process_seqs] Processed 696584 reads in 117.205 CPU sec, 4.113 real sec
[M::process] read 696626 sequences (100000124 bp) in 4.719 CPU sec, 5.235 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283913, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 346, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (516.06, 480.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.48, 140.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 267, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (283.58, 189.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 411, 2654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7556)
[M::mem_pestat] mean and std.dev: (1040.03, 1193.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696626 reads in 126.423 CPU sec, 4.331 real sec
sorting block 106, #reads = 1071889 mem = 536881995 peak = 807546880
[M::process] read 696482 sequences (100000228 bp) in 4.756 CPU sec, 5.385 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282765, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 387, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (445.70, 339.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.25, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 823, 2882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8512)
[M::mem_pestat] mean and std.dev: (1352.30, 1996.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 343, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4228)
[M::mem_pestat] mean and std.dev: (901.79, 958.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696482 reads in 113.635 CPU sec, 3.848 real sec
[M::process] read 697074 sequences (100000259 bp) in 4.494 CPU sec, 5.064 real sec...
sorting block 107, #reads = 1069259 mem = 536879182 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283573, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 556, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2796)
[M::mem_pestat] mean and std.dev: (630.92, 515.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (273.07, 141.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 375, 1951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5705)
[M::mem_pestat] mean and std.dev: (1099.05, 1272.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 363, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (579.42, 544.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697074 reads in 109.241 CPU sec, 3.530 real sec
[M::process] read 697170 sequences (100000084 bp) in 3.333 CPU sec, 3.745 real sec...
sorting block 108, #reads = 1071806 mem = 536879715 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283700, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 290, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (289.19, 157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.70, 141.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 542, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (411.08, 193.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 397, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (542.33, 455.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697900 sequences (100000106 bp) in 3.426 CPU sec, 3.659 real sec...
[M::mem_process_seqs] Processed 697170 reads in 113.069 CPU sec, 4.362 real sec
[M::process] read 705740 sequences (100000111 bp) in 2.518 CPU sec, 2.727 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284100, 37, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 420, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (483.82, 473.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.81, 140.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 746, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4725)
[M::mem_pestat] mean and std.dev: (1105.41, 835.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 458, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (663.62, 560.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705136 sequences (100000278 bp) in 1.643 CPU sec, 1.649 real sec...
[M::process] read 704030 sequences (100000218 bp) in 1.660 CPU sec, 1.664 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286534, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 247, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (266.94, 173.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 216, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (244.29, 124.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 706, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (709.17, 514.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 394, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (517.77, 524.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697900 reads in 209.885 CPU sec, 6.639 real sec
sorting block 109, #reads = 1070382 mem = 536882321 peak = 807546880
[M::mem_process_seqs] Processed 705740 reads in 137.967 CPU sec, 4.386 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 286948, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 505, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3423)
[M::mem_pestat] mean and std.dev: (600.53, 545.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (247.59, 126.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 674, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4133)
[M::mem_pestat] mean and std.dev: (900.94, 885.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 269, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (275.61, 125.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 110, #reads = 1065880 mem = 536878416 peak = 807546880
[M::process] read 702562 sequences (100000047 bp) in 3.026 CPU sec, 3.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 286650, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 270, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5576)
[M::mem_pestat] mean and std.dev: (934.14, 1254.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (251.38, 128.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 438, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (426.00, 407.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 381, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (434.80, 381.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704426 sequences (100000054 bp) in 1.860 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 705136 reads in 182.087 CPU sec, 5.782 real sec
[M::mem_process_seqs] Processed 704030 reads in 118.171 CPU sec, 3.998 real sec
sorting block 111, #reads = 1077330 mem = 536879000 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286135, 12, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 634, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (636.90, 448.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 703532 sequences (100000296 bp) in 2.394 CPU sec, 2.568 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (255.20, 130.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 707, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (631.18, 500.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 537, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (714.73, 563.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702462 sequences (100000002 bp) in 1.840 CPU sec, 1.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 287042, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 480, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (440.28, 300.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (249.11, 127.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 572, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (547.07, 369.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 328, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (343.04, 191.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702562 reads in 200.271 CPU sec, 6.604 real sec
[M::mem_process_seqs] Processed 704426 reads in 134.884 CPU sec, 4.303 real sec
sorting block 112, #reads = 1075877 mem = 536882229 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 286416, 25, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 272, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (459.03, 577.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (252.06, 129.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 289, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4408)
[M::mem_pestat] mean and std.dev: (779.17, 903.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 397, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (639.78, 641.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701170 sequences (100000135 bp) in 2.929 CPU sec, 3.123 real sec...
[M::process] read 701314 sequences (100000003 bp) in 1.877 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285941, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 261, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3814)
[M::mem_pestat] mean and std.dev: (601.04, 723.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.87, 131.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 726, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4787)
[M::mem_pestat] mean and std.dev: (1144.87, 1227.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 401, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (511.90, 419.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703532 reads in 194.421 CPU sec, 6.296 real sec
sorting block 113, #reads = 1073011 mem = 536879413 peak = 807546880
[M::mem_process_seqs] Processed 702462 reads in 121.496 CPU sec, 3.967 real sec
sorting block 114, #reads = 1074008 mem = 536879783 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285333, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 382, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (360.81, 262.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (259.55, 134.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 463, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (505.68, 455.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 713, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3440)
[M::mem_pestat] mean and std.dev: (635.83, 495.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699958 sequences (100000039 bp) in 2.933 CPU sec, 3.133 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285488, 17, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 395, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (690.74, 698.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (260.33, 135.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 442, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (616.94, 582.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 386, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (348.28, 214.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698930 sequences (100000086 bp) in 2.740 CPU sec, 2.737 real sec...
[M::mem_process_seqs] Processed 701170 reads in 197.441 CPU sec, 6.373 real sec
[M::mem_process_seqs] Processed 701314 reads in 129.301 CPU sec, 4.205 real sec
sorting block 115, #reads = 1073259 mem = 536880365 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285256, 22, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 334, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3830)
[M::mem_pestat] mean and std.dev: (630.00, 618.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (265.88, 138.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 490, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (434.83, 293.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 624, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (639.29, 449.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698158 sequences (100000197 bp) in 2.823 CPU sec, 3.014 real sec...
[M::process] read 697712 sequences (100000040 bp) in 1.760 CPU sec, 1.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284290, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 418, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (456.48, 336.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (268.59, 140.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (970, 1447, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (1109.64, 493.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 454, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (551.93, 460.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699958 reads in 188.547 CPU sec, 6.090 real sec
[M::mem_process_seqs] Processed 698930 reads in 121.927 CPU sec, 3.875 real sec
sorting block 116, #reads = 1073187 mem = 536878826 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284263, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 368, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6091)
[M::mem_pestat] mean and std.dev: (1152.93, 1402.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.65, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 623, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (682.86, 460.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 293, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (372.10, 272.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697286 sequences (100000024 bp) in 3.113 CPU sec, 3.306 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283063, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 345, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (444.05, 335.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (271.36, 139.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 693, 2273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5923)
[M::mem_pestat] mean and std.dev: (1033.64, 1136.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 340, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (528.75, 642.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697154 sequences (100000119 bp) in 2.010 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 698158 reads in 190.383 CPU sec, 6.133 real sec
sorting block 117, #reads = 1072145 mem = 536881641 peak = 807546880
[M::mem_process_seqs] Processed 697712 reads in 124.213 CPU sec, 3.969 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283487, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 574, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (701.39, 575.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.49, 140.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 995, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (911.25, 637.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 427, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (572.58, 445.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 118, #reads = 1070913 mem = 536883884 peak = 807546880
[M::process] read 696798 sequences (100000174 bp) in 2.895 CPU sec, 3.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283850, 39, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 422, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (588.97, 437.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.20, 140.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 236, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (257.52, 188.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 432, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (449.18, 264.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696400 sequences (100000233 bp) in 1.680 CPU sec, 1.681 real sec...
[M::mem_process_seqs] Processed 697286 reads in 190.288 CPU sec, 6.101 real sec
[M::mem_process_seqs] Processed 697154 reads in 124.424 CPU sec, 3.956 real sec
sorting block 119, #reads = 1072230 mem = 536879332 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283771, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 315, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (419.24, 305.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.28, 140.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 614, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (731.83, 702.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 320, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (426.21, 284.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695958 sequences (100000012 bp) in 2.891 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283211, 28, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 439, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264)
[M::mem_pestat] mean and std.dev: (685.00, 640.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.61, 139.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 318, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5228)
[M::mem_pestat] mean and std.dev: (1135.37, 1582.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 331, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (581.89, 707.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695546 sequences (100000175 bp) in 1.660 CPU sec, 1.664 real sec...
[M::mem_process_seqs] Processed 696798 reads in 186.459 CPU sec, 5.940 real sec
[M::mem_process_seqs] Processed 696400 reads in 119.825 CPU sec, 3.892 real sec
sorting block 120, #reads = 1072139 mem = 536882357 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282964, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 321, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (362.44, 257.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.98, 141.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 491, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (798.07, 780.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 313, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (415.79, 317.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695752 sequences (100000160 bp) in 3.096 CPU sec, 3.278 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282810, 35, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (314.26, 183.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.72, 141.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 479, 2141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5973)
[M::mem_pestat] mean and std.dev: (785.39, 877.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 442, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (412.57, 247.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695958 reads in 177.400 CPU sec, 5.721 real sec
[M::process] read 696310 sequences (100000132 bp) in 2.282 CPU sec, 2.334 real sec...
[M::mem_process_seqs] Processed 695546 reads in 123.244 CPU sec, 3.900 real sec
sorting block 121, #reads = 1073698 mem = 536879862 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283300, 26, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 394, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (584.73, 449.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.35, 142.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 547, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3977)
[M::mem_pestat] mean and std.dev: (758.46, 629.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 433, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (498.34, 395.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 518604 sequences (74389778 bp) in 2.624 CPU sec, 2.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283691, 26, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 295, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (538.34, 488.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.76, 143.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 272, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (284.18, 267.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 423, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (606.86, 517.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695752 reads in 172.302 CPU sec, 5.557 real sec
sorting block 122, #reads = 1073202 mem = 536882301 peak = 807546880
[M::mem_process_seqs] Processed 696310 reads in 113.347 CPU sec, 3.665 real sec
sorting block 123, #reads = 1073445 mem = 536881435 peak = 807546880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 210882, 12, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 323, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (335.38, 179.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.95, 140.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 979, 3372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9658)
[M::mem_pestat] mean and std.dev: (1422.25, 1654.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 547, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3938)
[M::mem_pestat] mean and std.dev: (904.19, 816.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 518604 reads in 75.195 CPU sec, 2.623 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 133045182
overall: 69540229120 mem 23341.824 user 1118.420 sys 860.571 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 860.602 sec; CPU: 24460.247 sec
sorting block 124, #reads = 813935 mem = 407517158 peak = 807546880
uniq header count 1
merging 125 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 7435771289
output reads: 134158744
bam_mem_sort: 125 calls 85.444 user 2.825 sys 88.421 real
bam_write: 125 calls 42.839 user 3.609 sys 48.415 real
execute: 1 calls 38.942 user 1.700 sys 908.116 real
merge_files: 1 calls 38.905 user 1.673 sys 46.957 real
parse_chunk: 1997 calls 93.596 user 23.484 sys 119.947 real
read_chunk: 5400 calls 65.144 user 52.604 sys 760.342 real
sort_block: 1 calls 52.196 user 51.882 sys 740.106 real
write_chunk: 3401 calls 38.522 user 1.306 sys 45.927 real
overall: 3118432256 mem 1884.910 user 104.949 sys 908.137 real
ls: cannot access '*.cram': No such file or directory