Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/foresight_panel_for_manta.bed
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4e/82af65452445e6b252c3eebbaa2b9b/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/protein_coding_genes.bed
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/41/fffb646dbc5138d457ad0e0feab8bf/659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz.tbi
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/41/fffb646dbc5138d457ad0e0feab8bf/659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/model.pkl
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4e/82af65452445e6b252c3eebbaa2b9b/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/cosmic_fusion.tsv.gz
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/MantaFusion/pon
==> STAGING COMPLETE (9 inputs)
[predict] Loading model from model.pkl …
36 features loaded
[predict] Loading PoN from pon …
1D bins: 43,871 2D pairs: 39,238
[predict] Loading COSMIC from cosmic_fusion.tsv.gz …
614 gene-pair orientations
[predict] Loading gene annotator from protein_coding_genes.bed …
[predict] Loading target panel from foresight_panel_for_manta.bed …
201,779 panel intervals across 26 contigs
[predict] Tumor sample ID: '659_eHw-T1-TDNA-1_B23MCVGLT4_1' Normal sample ID: '659_eHw-N1-BDNA-1_B23KFG5LT4_1'
[predict] Parsing VCF 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.annotated.vcf.gz …
12 calls parsed (after intergenic/same-gene/on_panel filter)
8 killed by hard filters → 4 surviving
is_paralog_of_higher_score_call=1 for 0/4 calls
[predict] Scored 4 calls: 2 PASS at threshold 0.15
After events_match dedup: 4 calls (2 PASS)
Final call set: 4 calls (2 PASS)
[predict] Writing 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.somatic_sv.scored.vcf.gz …
[predict] Writing 659_eHw-T1-TDNA-1_B23MCVGLT4_1_vs_659_eHw-N1-BDNA-1_B23KFG5LT4_1.manta_fusion.fusion_calls.tsv …
[predict] Done.